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It has been shown to be effective for weight loss in studies of patients with and without type 2 diabetes. Ozempic was actually developed as a treatment for type 2 diabetes because it helps lower blood glucose levels.
However, it was found to have a side effect: weight loss, which then continued when people without type 2 diabetes began prescribing Ozempic for weight loss.
Please note that only the injectable form, Wegovy, is approved for treating obesity (not the oral version).
In some cardiovascular disease outcome studies, semglutide has also been shown to reduce cardiovascular (CV) risk factors in patients with established CV disease.
How does Ozempic work for weight loss?
Once overweight or obese, the treatment proceeds as follows: Ozempic injections at the maximum dose (2.4 mg per week) help achieve these maximum weight loss goals.
However, patients should not start with the maximum dose immediately, as some patients may not tolerate it and may experience side effects such as nausea or vomiting. Therefore, a gradual increase in dose is recommended.
How semaglutide (Ozempic and Wegovy) works for weight loss is quite significant. GLP-1 is an important incretin hormone in humans. This means it increases insulin levels, inhibits glucagon release, and suppresses gluconeogenesis in the liver.
Semaglutide also causes delayed gastric emptying, decreased appetite, and decreased energy intake, thus having a beneficial effect on weight loss. It reduces the rate at which your stomach empties food after a meal (gastric emptying). The longer it takes for your stomach to empty, the longer the food stays in your stomach, making you feel full for longer.
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A study has shown that taking Ozempic under fasting conditions has the most optimal effect on achieving therapeutic concentration. Fasting for another half hour after taking the dose is beneficial.
In addition, Ozempic should be administered under the skin, in the subcutaneous or fatty layer, on your lower abdomen (around the waist), the front of your thighs, or your upper arm. Do not inject Ozempic into a muscle or vein.
Make sure to rotate (change) the injection site with each injection. Do not use the same injection site for every injection, or if you do choose the same injection site, do not use the same location each time.
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Both Ozempic and Wegovy are brand names for semaglutide. This is a long-acting GLP-1 receptor agonist that can be administered subcutaneously once a week.
It has been shown to be effective for weight loss in studies of patients with and without type 2 diabetes. Ozempic was actually developed as a treatment for type 2 diabetes because it helps lower blood glucose levels.
However, it was found to have a side effect: weight loss, which then continued when people without type 2 diabetes began prescribing Ozempic for weight loss.
Please note that only the injectable form, Wegovy, is approved for treating obesity (not the oral version).
In some cardiovascular disease outcome studies, semglutide has also been shown to reduce cardiovascular (CV) risk factors in patients with established CV disease.
How does Ozempic work for weight loss?
Once overweight or obese, the treatment proceeds as follows: Ozempic injections at the maximum dose (2.4 mg per week) help achieve these maximum weight loss goals.
However, patients should not start with the maximum dose immediately, as some patients may not tolerate it and may experience side effects such as nausea or vomiting. Therefore, a gradual increase in dose is recommended.
How semaglutide (Ozempic and Wegovy) works for weight loss is quite significant. GLP-1 is an important incretin hormone in humans. This means it increases insulin levels, inhibits glucagon release, and suppresses gluconeogenesis in the liver.
Semaglutide also causes delayed gastric emptying, decreased appetite, and decreased energy intake, thus having a beneficial effect on weight loss. It reduces the rate at which your stomach empties food after a meal (gastric emptying). The longer it takes for your stomach to empty, the longer the food stays in your stomach, making you feel full for longer.
This results in less hunger and appetite. In general, patients taking Ozempic or Wegovy eat less and therefore lose weight.
Ozempic not only affects gastric emptying, but also the GLP-1 receptors in the hypothalamus, which are responsible for regulating food intake in the nervous system. This reduces feelings of hunger and appetite in people with obesity.
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Where do I inject Ozempic?
A study has shown that taking Ozempic under fasting conditions has the most optimal effect on achieving therapeutic concentration. Fasting for another half hour after taking the dose is beneficial.
In addition, Ozempic should be administered under the skin, in the subcutaneous or fatty layer, on your lower abdomen (around the waist), the front of your thighs, or your upper arm. Do not inject Ozempic into a muscle or vein.
Make sure to rotate (change) the injection site with each injection. Do not use the same injection site for every injection, or if you do choose the same injection site, do not use the same location each time.
Dose titration is necessary with Ozempic. This means that patients should start treatment with 0.25 mg, then increase to 0.5 mg, and then to 1 mg, with an interval of 4 weeks. The Ozempic pen (red and blue) is available in a strength of 1.34 mg/ml.
The red pen delivers a starting dose of 0.25 mg and a maintenance dose of 0.5 mg. The blue pen, on the other hand, is designed for 1.0 mg (maximum maintenance dose) of semaglutide.
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When patients first start taking Ozempic, side effects such as diarrhea, nausea, or vomiting may occur. However, these may disappear over time as the patient adjusts to the medication.
To help the body adjust to the medication and dosage, it is recommended to avoid fried foods, fatty foods, such as fast food, and foods high in sugar. Ozempic and fatty foods are not friends – they can worsen side effects.
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